FIBERGRAFT® BG Morsels

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Prosidyan’s revolutionary and proprietary manufacturing process has led to an evolution in synthetic bone grafting. Utilizing microscopic fibers of bioactive glass, FIBERGRAFT® BG Morsels leverage the direct connectivity of fibers with exponentially increased surface area and optimized resorption rates. The result is a 100% pure bioactive bone graft substitute with an ultra-porous scaffold. FIBERGRAFT® truly redefines porosity and connectivity.

FIBERGRAFT® BG Morsels is a purely synthetic bone graft substitute made entirely from crystalline 45S5 bioactive glass. Each granule of FIBERGRAFT® BG Morsels features a porous outer shell encasing an intricate nest of fibers and microspheres.

FIBERGRAFT® is designed to have adequate structural integrity for its application as a bone graft substitute material, while optimizing radiopacity and resorption.

FIBERGRAFT® BG Morsels, 100% synthetic bone graft substitute, made from 45S5 bioactive glass fibers.

Continuous Porosity
The porosity created by the fibers is continuous and completely inter-connected and there are no physical interruptions. The amount and range of porosity in FIBERGRAFT® BG Morsels has been engineered by controlling the size and quantities of fibers and microspheres, and by the optimized design of its porous outer shell.

Increased Surface Area
FIBERGRAFT®’s proprietary design creates a mechanical and biomechanical environment providing maximized surface area for HA deposition and controlled resorption. Utilizing solid or porous structures, the concentrated fibers inside FIBERGRAFT® BG Morsels offer vastly increased surface area.

Direct Connectivity
Bioactive glass fibers in FIBERGRAFT® BG Morsels provide a unique and exclusive direct connectivity inside a bone void defect. Unlike traditional bone grafts, the connectivity of the fibers provides an uninterrupted corridor for cell growth along their length.

Differential Rate of Resorption
Each BG Morsel is comprised of a range of fibers and microspheres. The smaller fibers and microspheres resorb quicker, while the larger structures resorb over an extended period of time. This optimized mode of differential resorption creates a favorable environment during all phases of bone healing.

Pre-Clincial Studies

EARLY HA DEPOSITION

FIBERGRAFT® was immersed in Simulated Body Fluids at 37° C to test for Hydroxyapatite (HA) deposition on its surface. HA Crystals were observed on the FIBERGRAFT® surface within 24 hours of immersion.

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GLP SHEEP STUDY
Micro CT Images of Bone Formation at Defect Site

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GLP SHEEP STUDY
Histology Images of Bone Formation at Defect Site
(Goldener’s Trichrome Stain)

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RABBIT POSTEROLATERAL SPINE FUSION STUDY

BG MORSELS + BONE MARROW ASPIRATE + AUTOGRAFT

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COMPETITOR + AUTOGRAFT

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Points to Note

Model: Rabbit Posterolateral spine fusion
At 26 weeks 100% fusion in BG Morsels
At 26 weeks, no fusion in competitor group

ORDERING INFORMATION

FIBERGRAFT® BG Morsels

4600-0100
Large – 11CC
4600-0050
Medium – 6CC
4600-0020
X-Small – 2CC

Rx Only: Federal law restricts this device to sale by or on the order of a physician.
This website provides an overview of FIBERGRAFT® BG Morsels. Prior to use, please see the complete Instructions for Use for the device indications, contraindications, warnings, precautions and directions for use. For additional information, please call Prosidyan at 908.517.3666.